Health Investment & Finance








Pfizer Inc. is the world largest pharmaceutical company. Founded in 1849, its headquarters today is based in New York, NY.

Pfizer is a multinational and multi-product company, which engages in the discovery, development, manufacture, and marketing of prescription medicines for humans and animals worldwide.

It serves doctors, nurse practitioners, physician assistants, pharmacists, hospitals, pharmacy benefit managers, managed care organizations, and government agencies.

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From BusinessWeek

Pfizer, Inc. engages in the discovery, development, manufacture, and marketing of prescription medicines for humans and animals worldwide.

Its Pharmaceutical segment offers Lipitor for elevated cholesterol levels in the blood; Norvasc for hypertension; Caduet for cardiovascular events; Chantix/Champix for smoking cessation; Lyrica for neuropathic pain; Geodon/Zeldox, a psychotropic agent; Aricept for Alzheimer’s disease; and Zoloft for various disorders.

It also offers Celebrex for arthritis pain, and inflammation and acute pain; Vfend for esophageal candidiasis and blood stream infections; Zyvox for bacterial infections; and Selzentry/Celsentri for adults infected with only CCR5-tropic HIV-1 detectable.

In addition, this segment provides Viagra for erectile dysfunction; Detrol for overactive bladder; Camptosar for metastatic colorectal cancer; Sutent, an oral multi-kinase inhibitor; Xalatan/Xalacom for open-angle glaucoma and ocular hypertension; Genotropin for growth disorders; and Zyrtec/Zyrtec for allergies and hives.

The company’s Animal Health segment offers parasiticides, anti-inflammatories, antibiotics, vaccines, antiemetics, and anti-obesity agents.

It also provides Revolution/Stronghold for dogs and cats; Rimadyl for pain and inflammation associated with canine osteoarthritis and soft tissue orthopedic surgery; Clavamox/Synulox for skin and soft tissue infections; RespiSureOne/StellamuneOne to prevent pneumonia in swine; Bovi-Shield Gold for reproductive and respiratory protection; Dectomax, an injectable and pour-on formulations; Draxxin, an antibiotic for infections in cattle and swine; and Excede to treat infections.

Pfizer, Inc. is involved in contract manufacturing and bulk pharmaceutical chemicals businesses. It serves doctors, nurse practitioners, physician assistants, pharmacists, hospitals, pharmacy benefit managers, managed care organizations, and government agencies. The company was founded in 1849 and is headquartered in New York, New York.

More from Reuters

Pfizer Inc. (Pfizer), incorporated on June 2, 1942, is a research-based, global pharmaceutical company. The Company discovers, develops, manufactures and markets prescription medicines for humans and animals. It operates in two business segments: Pharmaceutical and Animal Health. The Company also operates several other businesses, including the manufacture of gelatin capsules, contract manufacturing and bulk pharmaceutical chemicals. In June 2008, Pfizer completed the acquisition of all remaining outstanding shares of common stock of Encysive Pharmaceuticals, Inc. through a merger of Pfizer's wholly owned subsidiary, Explorer Acquisition Corp., with and into Encysive.

In January 2008, the Company completed the acquisition of Coley Pharmaceutical Group, Inc., a company whose area of capability is immunotherapy with emphasis on Toll-like receptor research and development. In January 2008, it completed the acquisition of CovX Research LLC, which is a biotherapeutics company focused on preclinical oncology and metabolic research and a developer of a technology platform.

Pharmaceutical

The Company’s Pharmaceutical business segment includes products that treat cardiovascular and metabolic diseases, central nervous system disorders, arthritis and pain, infectious and respiratory diseases, Urology; oncology; ophthalmology and endocrine disorders. As of October 2007, the company’s portfolio of medicines included seven medicines. Lipitor, for the treatment of elevated cholesterol levels in the blood, is a treatment used for lowering cholesterol. Norvasc is a medicine for treating hypertension. Caduet is a single pill therapy combining Lipitor and Norvasc for prevention of cardiovascular events. Chantix/Champix is a prescription treatment for smoking cessation became available to patients in the United States in August 2006. It also is available in over 20 European markets, a well as Canada, Australia, Korea, Brazil and Mexico.

Lyrica is an adjuctive therapy for adults with partial onset epileptic seizures. In June 2007, Lyrica was approved in the United States for the management of fibromyalgia, one of the chronic pain conditions. Geodon/Zeldox, a psychotropic agent, is a dopamine and serotonin receptor antagonist indicated for the treatment of schizophrenia and acute manic or mixed episodes associated with bipolar disorder. Aricept, discovered and developed by Eisai Co., Ltd., is a medicine to treat symptoms of Alzheimer’s disease. The Company co-promotes Aricept with Eisai in the United States, and other countries and has a license to sell this medicine in certain other countries. Zoloft is indicated for the treatment of depressive disorder, panic disorder, obsessive-compulsive disorder in adults and children, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD) and social anxiety disorder (SAD). Celebrex is for the treatment of osteoarthritis, adult rheumatoid arthritis, acute pain, menstrual pain and familial adenomatous polyposis. Celebrex also was approved by the FDA in July 2005, and in Europe in February 2007, for the treatment of ankylosing spondylitis, a form of spinal arthritis, and in December 2006, for the treatment of juvenile rheumatoid arthritis.

Vfend is a treatment that can be administered orally or intravenously for certain serious and potentially fatal fungal infections, for the treatment of esophageal candidiasis and for the treatment of certain blood stream infections in non-neutropenic patients (those without low white blood cell counts). Vfend is also available in an oral-suspension formulation suitable for patients unable to swallow the tablet form. Zyvox is for the treatment of bacterial infections, which are caused by drug-resistant bacteria, and the treatment of diabetic foot infections. Zyvox is available in intravenous, tablet and oral-suspension formulations. Selzentry/Celsentri was approved in the United States in August 2007, and in Europe in September 2007, and is indicated for combination anti- retroviral treatment of treatment-experienced adults infected with only CCR5-tropic HIV-1 detectable, who have evidence of viral replication and has HIV-1 strains resistant to multiple anti-retroviral agents. Viagra remains the treatment for erectile dysfunction (ED). Detrol is a product for the treatment of overactive bladder. Detrol LA is an extended-release formulation of this medicine, taken once a day.

Camptosar, which is marketed under the name Campto in many countries outside the United States, is indicated as first-line therapy for metastatic colorectal cancer in combination with five-fluorouracil and leucovorin. Sutent is an oral multi-kinase inhibitor that combines anti-angiogenic and anti-tumor activity to inhibit the blood supply to tumors. Sutent was approved by the FDA and launched in the United States in January 2006, for renal cell carcinoma, including metastic renal cell carcinoma, and gastrointestinal stromal tumors (GIST) after disease progression on or intolerance to imatinib mesylate. In January 2007, Sutent received marketing authorization and extension of the indication to first-line treatment of metastatic renal cell carcinoma, as well as approval for second-line treatment of GIST in the European Union.

Xalatan/Xalacom is a glaucoma medicine used to treat open-angle glaucoma and ocular hypertension. Genotropin is a human recombinant growth hormone. Genotropin is used for the treatment of various growth disorders in children and adults. Novo Nordisk has granted the Company a license to sell Genotropin in the United States. Zyrtec is for the treatment of year-round indoor and seasonal outdoor allergies and hives in adults and children. The Company lost United States exclusivity for Zyrtec in January 2008. Since the Company sold its rights to market Zyrtec over-the- counter in connection with the sale of its Consumer Healthcare business, Pfizer ceased selling this product in January 2008.

Animal Health

Pfizer’s Animal Health business segment discovers, develops and sells products for the prevention and treatment of diseases in livestock and companion animals. Among the products the Company markets are parasiticides, anti-inflammatories, antibiotics, vaccines, antiemetics and anti-obesity agents. Parasiticides is a segment of the animal health market for companion animals, consisting of medicines for the control of parasites, such as fleas and heartworm. The Company’s product, Revolution, is the parasiticide for dogs and cats. Rimadyl relieves pain and inflammation associated with canine osteoarthritis and soft tissue orthopedic surgery. Rimadyl is an arthritis pain medication prescribed by veterinarians available in chewable tablets, regular caplets and in an injectable formulation. Clavamox/Synulox is an antibiotic for skin and soft tissue infections in dogs and cats. Pfizer’s vaccine portfolio for livestock includes RespiSureOne/StellamuneOne, a single-dose vaccine used to prevent pneumonia in swine, and Bovi-Shield Gold, a cattle vaccine for reproductive and respiratory protection. Dectomax injectable and pour-on formulations remove and control internal and external parasites in beef cattle. Draxxin is an effective and convenient single dose antibiotic used to treat infections in cattle and swine. Excede is an effective and convenient single-dose antibiotic used to treat infections in dairy cows, beef cattle and swine.

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